涂景,男,1982年生,工学博士,教授、博士生导师,东南大学青年首席教授,国家高层次青年人才,江苏省杰出青年基金获得者。现任yL23411永利官网登录院长,中国医疗器械行业协会产教融合专委会秘书长。本硕博就读于yL23411永利官网登录,2011年获工学博士学位。荣获国家教学成果二等奖1项、东南大学首届“杰出教学奖”。
每年拟招收2名博士研究生、3-5名硕士研究生,欢迎生物医学工程、生物信息学专业及具有生物、医学、电子信息和计算机等相关专业背景的同学报考。同时欢迎优秀博士毕业生进站开展博士后研究!
Email:jtu@seu.edu.cn
研究方向
1.DNA测序技术(高通量测序,单细胞测序,单分子测序等)
2.生物信息学(基因组、转录组分析,测序信息学等)
3.核酸分析技术(基因芯片,微流控系统,纳米孔传感器等)
研究成果
近年来,主持国家重点研发计划课题1项,主持国家自然科学基金项目4项,主持省部级项目及其他项目6项,作为项目骨干参与多项国家重点研发计划、科技部973计划、国家重大科研仪器研制专项等重要科研项目。以第一作者/通讯作者在Nature Communications、Cell genomics和Nucleic Acids Research等知名期刊发表SCI论文近50余篇,获国家发明专利授权10余件。担任Nature Aging、Bioinformatics和Lab on a Chip等国际学术期刊审稿人。近五年,指导江苏省优秀本科毕业论文2篇、江苏省优秀本科毕业论文团队1支,指导东南大学优秀硕士学位论文1篇,3名研究生入选江苏省研究生培养创新工程。
近年部分代表性论文
1.Qiao Y, Cheng TG, Miao ZK, Cui Y, Tu J*: Recent Innovations and Technical Advances in High-Throughput Parallel Single-Cell Whole-Genome Sequencing Methods. Small Methods, 2024, 2400789.
2.Fu JY, Tu J*: Extracellular RNA: A new perspective on the human pre-implantation embryos. Cell Genomics, 2024, 4: 100472.
3.Qiao Y#, Zhang QD#, He YK, Cheng TG, Tu J*: A simple joint detection platform for high-throughput single-cell heterogeneity screening. Talanta, 2024, 269, 125460.
4.Lu N, Qiao Y, An PF, Luo JJ, Bi CW, Li MS, Lu ZH*, Tu J*: Exploration of whole genome amplification generated chimeric sequences in long-read sequencing data. Briefings in Bioinformatics, 2023, 24(4): bbad275.
5.Fu JY, Wu LL, Hu G, Li FY, Ge QY, Lu ZH*, Tu J*: Solid-state Nanopore Analysis on Conformation Change of DNA Polymerase I induced by DNA Substrate. Analyst, 2022, 147, 3087-3095.
6.Tu J*, Qiao Y, Xu ZY, Lu N, Long NY, Lu ZH*: dCITI-Seq: Droplet Combinational Indexed Transposon Insertion Sequencing. Analytical and Bioanalytical Chemistry, 2022, 414: 2661-2670.
7.Tu J*, Duan MQ, Liu WL, Lu N, Zhou Y, Sun X, Lu ZH*: Direct genome-wide identifying of G-quadruplex structures by whole-genome resequencing. Nature Communications, 2021, 12: 6014.
8.Huang MT#, Yang YX#, Wen XZ#, Xu WQ, Lu N, Sun X, Tu J*, Lu ZH: Inferring single cell expression profiles from overlapped pooling sequencing data with compressed sensing strategy. Nucleic Acids Research, 2021, 49(14): 7995-8006.
9.Qiao Y, Liu WL, Lu N, Xu ZY, Tu J*, Lu ZH*: Cyclical concentration adjusting accelerates the time-consuming multiple displacement amplification. Analytica Chimica Acta, 2021, 1141(1): 173-179.
10.Hu G, Fu JY, Qiao Y, Meng H, Wang ZL, Tu J*, Lu ZH*: Molecular dynamics discrimination of the conformational states of Calmodulin through solid-state nanopore. Physical Chemistry Chemical Physics, 2020, 22(1), 19188-19194.